Dupuytren’s disease causes a gradual thickening and tightening of tissue beneath the skin of the palm, pulling one or more fingers into a bent position that cannot be straightened. It is an unpredictable condition in terms of the speed and extent of progression and also the response to treatment. Whilst it is not a dangerous condition but it tends to progress without treatment to disrupt or remove the thickened tissue.

Understanding The Condition – What is Dupuytren’s Disease?
Dupuytren’s disease is a benign but progressive condition affecting the palmar fascia — the layer of fibrous tissue that lies beneath the skin of the palm and fingers. It is inherited and it is more commonly seen in men with 5 males for every female affected.
The palmar fascia layer starts to thicken in places forming firm nodules or sometimes little crevices. Often it will progress to form cords that tether the skin and pull finger joints into a bent position.
It can be sore when it first starts to develop but most cases do not experience pain.
The little or ring fingers are most commonly affected but other fingers or thumb can also be involved. A few patients are unfortunate enough to have all of their fingers and thumbs involved but it is much more usual to find one or two fingers with dupuytren’s disease
The speed and extent of progression is variable – some cases may never develop more than a nodule in the palm or the finger, some will develop contracture over many years and others may progress to finger contractures within a few months.
Each finger has 3 joints, here again there is variability with the number of joints affected and the extent to which each joint becomes involved.
With increasing contracture angles patients will start to find that manual tasks and activities become awkward. Putting on gloves, shaking hands, washing face, reaching into a drawer or pocket are all common activities which can be affected.
Signs & Symptoms – What to Look For
- A firm lump or cord in the palm, just under the surface of the skin.
- Puckering, pitting or dimpling of the skin in the palm
- The cord or lump appears to prevent full straightening of adjacent finger(s) – this cannot be overcome with stretching or exercising
- Dupuytren’s disease is not usually painful; if you have pain or tingling it could be that you have another common hand condition (carpal tunnel, arthritis or trigger finger for example)
Causes and Risk Factors
Genetic Predisposition
Dupuytren’s disease is inherited from one of your blood relatives although it doesn’t always follow a consistent pattern of inheritance – if you have it, it is not necessarily the case that your mum or dad will have had it. It is sometimes called the “Viking disease” due to its high prevalence in Northern European populations.
Sex & Age
Dupuytren’s disease affects more men than women, with overall male-to-female ratios ranging of approx 5:1. However, the discrepancy is age-dependent; the disease presents earlier in men, usually aged 55-70, but the gender gap narrows significantly, approaching 1:1 by age 80.

When is Treatment Needed?
Not all Dupuytren’s disease requires treatment. In the early stages when only a nodule is present and there is no contracture the condition is monitored rather than treated.
Treatment is generally considered when there is 30 degrees or more of contracture at any of the finger joints.
Response to treatment is not easy to predict but generally speaking higher contracture angles and longer duration before treatment make for less optimistic outcomes.
Treatment Options – Non-surgical treatments
Radiotherapy: there is some evidence that radiotherapy may reverse or slow progression of early stage disease in approximately 50% of patients.
Collagenase injections: these were available in the early 2000’s but were withdrawn from European markets in 2019 because the treatment benefit was not better than other types of treatment and cost was higher.
Minimally Invasive – Needle Fasciotomy
Also known as percutaneous needle aponeurotomy
Needle fasciotomy is the least invasive treatment for Dupuytren’s contracture. Using a hypodermic needle inserted through the skin at multiple points, the Dupuytren’s cord is weakened and disrupted. There is no surgical incision, simply a line of small skin punctures and sometimes a small hole. No stitches are required.
The procedure typically takes 20 minutes and it is awake surgery using local anaesthetic injections at the start.
The small skin puncture sites heal quickly, there is a sticking plaster and patients can commence gentle activities straight away.
Needle fasciotomy is mainly effective in treating contractures which arise from cords in the palm and which bend the metacarpophalangeal (MCP) joint (this is the joint which connects the finger to the palm). If there are significant contractures at the mid-joint of the finger (PIP Joint) these do not typically respond to needle fasciotomy.
Because it does not remove any tissue it has a recurrence rate of 50% at 2 years but its convenience often makes it an advantageous choice and fingers on both sides can be treated simultaneously if necessary. It can be repeated in the future or other treatments can be used subsequently.
Anaesthetic: Local anaesthetic
Duration: 20 minutes
- Stitches: None
- Recovery: Minimal down-time
Hand Therapy: Not usually required
Recurrence: 50% at 2 years
- Indication: Mainly MCP joint
Standard Surgery – Dupuytren’s Fasciectomy
Fasciectomy is the most commonly performed surgical treatment for Dupuytren’s disease and is considered to be the standard for most patients with established Dupuytren’s contracture. Curved or zig-zag incisions are made in the palm and finger. This exposes the Dupuytren’s tissue and allows it to be carefully dissected and removed. There are important nerves and vessels immediately adjacent and in some cases the Dupuytren’s tissue wraps around or adheres to these making dissection complex.
It can be done with awake or asleep surgery. Dressings and bandaging are used and sometimes a splint as well. The surgery itself causes tissue disturbance and scar formation. The strength and duration of this response is very variable from one patient to another. You will need hand therapy as part of your treatment and this is usually commenced within a fortnight of operation. Early movement and activities are encouraged but it will take 6-12 months for all the swelling to settle and for the final outcome to be realised.
The MCP joint will usually correct well but the PIP joint is much less predictable and typically some contracture will persist. A small proportion of patients will have a difficult recovery and may end up with minimal benefit.
Anaesthetic: Local or general
Duration: Approx 90 minutes per finger
Hospital Stay: Day case
Stitches: Yes
Recovery: Hand therapy and often splints
Recurrence: 20% at 2 years
- Indication: Standard treatment for most Dupuytren’s cases
Severe or Recurrent Disease – Dermofasciectomy
Where there is complex or recurrent disease, Dermofasciectomy may be recommended. This means that a section of skin is removed and a skin graft is used to make up for the gap that results.
The rationale is that skin from outside the palm does not carry Dupuytren’s-affected cells, so grafted skin is significantly less likely to develop new disease.
These cases are typically more complex for surgical dissection and there is additional complexity to harvest (usually taken from the arm) and place the skin graft.
The healing process is more complex and it relies upon the graft ‘taking’.
Recovery is longer and the outcome is more variable than for standard fasciectomy especially if the graft doesn’t take. It will take approximately 1 year for tissues to fully settle and for the graft to mature.
Anaesthetic: Local or general
Duration: 120 minutes per finger
Hospital Stay: Day case
Stitches: Yes
Recovery: Hand therapy and splints
Recurrence: Usually used to treat recurrent disease
Indication: Recurrent disease, severe disease
Frequently Asked Questions
Can Dupuytren’s disease be cured?
There is no cure for Dupuytren’s disease — it is a lifelong condition and any treatment addresses the contracture rather than the underlying tendency to form diseased fascia. Recurrence is therefore possible with all treatments. Managing expectations around recurrence is an important part of the pre-operative discussion. Many patients, however, go many years without recurrence requiring further intervention.
Which treatment is right for me?
The choice depends on several factors: the degree and location of contracture (MCP joint vs PIP joint), whether this is primary or recurrent disease, your age, general health, occupation and personal preferences. Needle fasciotomy suits milder MCP contractures or those preferring to avoid surgery. Fasciectomy is appropriate for most patients with established contracture. Dermofasciectomy is usually reserved for recurrent disease or with complex disease.
Will my finger straighten completely after surgery?
Correction at the MCP joint (knuckle) is usually excellent and near-complete. Correction at the PIP joint (the middle joint of the finger) is less predictable — particularly if the contracture is severe or has been present for many years — due to secondary changes in the joint capsule, skin and soft tissues. This is why early treatment, before the PIP joint becomes severely contracted, generally produces better outcomes. Even partial correction can significantly improve function and comfort.
How long does recovery take?
After needle fasciotomy, most patients can use the hand for light activities straight away. There is considerable variability with recovery after open surgery. There is bandaging and dressings which will restrict many activities for at least 2 weeks. The finger / hands will be swollen and stiff and uncomfortable for many more weeks although movement and activities are encouraged especially once the surgical wounds have healed over (2-3 weeks). Hand therapy is vital after fasciectomy and dermofasciectomy and this will involve regular visits during the initial 2 months from operation.
What happens if Dupuytren’s comes back?
Recurrent Dupuytren’s contracture can be treated again. The options available depend on what previous treatment has been performed, the degree of recurrence and the condition of the tissues. Recurrent disease in previously operated tissue is more technically demanding, as the anatomy is often distorted by scar tissue, and the risk of complications (including nerve and vessel injury) is higher. Dermofasciectomy is often the preferred option for recurrent disease.
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